Ciro Ferrara and Juventus maintains their perfect start to the season after travelling to the Olimpico in Rome and departing with three Serie A points after a Diego-inspired 3-1 victory over Francesco Totti's Roma. Inter Milan thrased 10-man Milan 4-0 in the Milanese derby.
Sampdoria and Genoa share the top of the table honours with two wins from two games after Italy hopeful Antonio Cassano orchestrated his sides 3-1 win over Udinese.
New Genoa signing Moretti scored the winner after defeating Atalanta in Bergamo.
Other Results
Bari 0 Bologna 0
AC Milan 0 Inter Milan 4 (Motta, Milito, Maicon, Stankovic)
Roma 1 (De Rossi) Juventus 3 (Diego 2, Melo)
Atalanta 0 Genoa 1 (Moretti)
Cagliari 1 (Jeda) Siena 3 (Calaio 2, Reginaldo)
Chievo 1 (Pellissier) Lazio 2 (Cruz 2)
Fiorentina 1 (Jovetic) Palermo 0
Napoli 3 (Quagliarella 2, Hamsik) Livorno 1 (C.Lucarelli)
Parma 2 (Galloppa, Paloschi) Catania 1 (Biaganti)
Sampdora 3 (Pazzini, Mannini, Cassano) Udinese 1 (Di Natale)
Seria A Table 2009/2010 after Round 2
| Team | P | W | D | L | GF | GA | GD | Pts | |
| 01 | Sampdoria | 2 | 2 | 0 | 0 | 5 | 2 | 3 | 6 |
| 02 | Juventus | 2 | 2 | 0 | 0 | 4 | 1 | 3 | 6 |
| 03 | Genoa | 2 | 2 | 0 | 0 | 4 | 2 | 2 | 6 |
| 04 | Lazio | 2 | 2 | 0 | 0 | 3 | 1 | 2 | 6 |
| 05 | Internazionale | 2 | 1 | 1 | 0 | 5 | 1 | 4 | 4 |
| 06 | Parma | 2 | 1 | 1 | 0 | 4 | 3 | 1 | 4 |
| 07 | Fiorentina | 2 | 1 | 1 | 0 | 2 | 1 | 1 | 4 |
| 08 | Siena | 2 | 1 | 0 | 1 | 4 | 3 | 1 | 3 |
| 09 | Napoli | 2 | 1 | 0 | 1 | 4 | 3 | 1 | 3 |
| 10 | Palermo | 2 | 1 | 0 | 1 | 2 | 2 | 0 | 3 |
| 11 | AC Milan | 2 | 1 | 0 | 1 | 2 | 5 | -3 | 3 |
| 12 | Bari | 2 | 0 | 2 | 0 | 1 | 1 | 0 | 2 |
| 13 | Bologna | 2 | 0 | 2 | 0 | 1 | 1 | 0 | 2 |
| 14 | Udinese | 2 | 0 | 1 | 1 | 3 | 5 | -2 | 1 |
| 15 | Livorno | 2 | 0 | 1 | 1 | 1 | 3 | -2 | 1 |
| 16 | Cagliari | 2 | 0 | 1 | 1 | 1 | 3 | -2 | 1 |
| 17 | Catania | 2 | 0 | 0 | 2 | 2 | 4 | -2 | 0 |
| 18 | Chievo | 2 | 0 | 0 | 2 | 1 | 3 | -2 | 0 |
| 19 | Atalanta | 2 | 0 | 0 | 2 | 0 | 2 | -2 | 0 |
| 20 | AS Roma | 2 | 0 | 0 | 2 | 3 | 6 | -3 | 0 |